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Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins

Longer studies (1 year) showed 43.8% fewer flare-ups and improved lung flow by nearly 97% (NIH)

The interaction of carotenoids with Nrf2 enhances its translocation into the nucleus, which in turn activates glutathione S-transferases, an important family of detoxification enzymes that suppresses the level of oxidative stress

Carboplatin was preferred as the platinum agent of choice over cisplatin in advanced ovarian cancer in palliative settings owing to its less nephrotoxicity and neurotoxicity when compared to cisplatin [105]